Spravato (Esketamine) Treatment For Depression

With fewer depression symptoms, you may begin to

Feel like yourself again.

SPRAVATO®, a nasal spray that works differently than traditional antidepressants, and find out if SPRAVATO® is right for you.

spravato depression and anxiety care at serene health and wellness

You are not alone.
Millions of Americans suffer from treatment-resistant depression.

Did You Know?

Major depressive disorder (MDD), also known as clinical depression, is one of the most common mental health disorders in the United States, affecting more than 21 million adults.

Clinical depression symptoms may include depressed mood, loss of interest in daily activities, change in sleep, appetite or weight, fatigue, diminished concentration or slowed thoughts, feelings of worthlessness and/or suicidal ideation.

When two or more antidepressants don’t provide relief for clinical depression, this is commonly known as treatment-resistant depression.

According to a study, 1 in 3 people did not experience a reduction in their depressive symptoms when taking antidepressants alone.

Cycling through medications can be frustrating. If two or more antidepressants haven’t worked for you, ask your healthcare provider about SPRAVATO®.

Over 100,000+ people in the United States have been treated with SPRAVATO®.

Is SPRAVATO® Right for You?

SPRAVATO® may be an option if:

  • You have tried multiple antidepressants without adequate relief

  • Depression continues to affect your quality of life

  • You are seeking additional mental health treatment options

A consultation allows us to review your medical history, current medications, and symptoms to determine whether SPRAVATO® is an appropriate part of your care.

What Is SPRAVATO® and How Does It Work?

SPRAVATO® is the only FDA-approved nasal spray for adults with treatment-resistant depression that can be taken with or without an oral antidepressant, giving you more options and flexibility.

SPRAVATO® can help reduce depression symptoms when antidepressants haven’t worked well for you.

This unique mechanism allows SPRAVATO® to support brain pathways associated with both depression. It is always used alongside an oral antidepressant and administered under medical supervision as part of a comprehensive mental health treatment plan.

What Is a Treatment Like?

SPRAVATO® treatments are performed in our office so your safety and comfort can be closely monitored.

During each visit:

  • You will self-administer the nasal spray under supervision
  • You will relax in a private room for approximately two hours
  • Many patients choose to rest, listen to music, or a calming podcast
  • Our team will check in with you regularly and monitor your blood pressure

At the end of the observation period, you will be evaluated once more before discharge. Due to the sedating effects of the medication, you will need someone to drive you home after your appointment.

Treatment Schedule

Most patients follow a structured treatment plan:

  • Twice weekly treatments for the first four weeks

  • Once weekly for the next four weeks

  • Then every two weeks for maintenance

As symptoms stabilize, treatments may be spaced out further based on individual progress.

When Will I Notice Improvement?

Response to SPRAVATO® varies. Some patients experience improvement in mood symptoms within the first few treatments, while others may notice gradual changes over several weeks.

Patients often report:

  • Improved mood and emotional balance

  • Reduced mental overwhelm

  • Increased energy and motivation

  • Greater enjoyment in daily activities

Our team monitors your response closely and adjusts your treatment plan as needed.

Compassionate Mental Health Treatment at Serene Health & Wellness

At Serene Health & Wellness, we believe treatment for depression should feel personal, thoughtful, and human. We focus on listening, education, and individualized care so you never feel rushed or overlooked.

If depression has left you feeling stuck or overwhelmed, help is available. We are here to walk alongside you and help you find relief.

Contact Serene Health & Wellness today to learn more about SPRAVATO® treatment and schedule a consultation.

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